منابع مشابه
New hope for haplotype mapping
The systematic analysis of polymorphisms across large parts of the human genome has begun to provide the first information on haplotypes and the problem of linkage disequilibrium across large genomic regions. These data suggest that significant regions of the genome show highly conserved haplotypes, potentially enhancing the ability to detect disease associations.
متن کاملGene Mapping by Haplotype Pattern Mining
We describe a new method for linkage disequilibrium mapping, Haplotype Pattern Mining (HPM). The method is based on discovering recurrent patterns, inspired by data mining methods. We define a class of useful haplotype patterns in genetic case-control data, and give an algorithm for finding disease-associated haplotypes. The haplotypes are ordered by their strength of association to the phenoty...
متن کاملHaplotype mapping in epilepsy genetics and pharmacogenetics
Despite the success achieved in identifying mutations causing Mendelian forms of epilepsy, little progress has been made in illuminating variation contributing to the development of more common forms of the condition. The aim of this thesis was to improve methodology that would aid the detection of variation functional in the development and treatment of common forms of epilepsy. Attempted repl...
متن کاملThe International HapMap Project
The goal of the International HapMap Project is to determine the common patterns of DNA sequence variation in the human genome and to make this information freely available in the public domain. An international consortium is developing a map of these patterns across the genome by determining the genotypes of one million or more sequence variants, their frequencies and the degree of association...
متن کاملSummer Project Robotic mapping
Robotic mapping is a problem of building models (maps) of environment from sensor measurements by mobile robots. Models of environment are the basic knowledge an autonomous robot must possess in order to carry out any higher level tasks like planning. Therefore robotic mapping is one of the most intensively studied problems of mobile robotics in recent years. The mapping problem is also known a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of Ibadan Postgraduate Medicine
سال: 2007
ISSN: 1597-1627
DOI: 10.4314/aipm.v2i2.39089